Ireland’s Specialist in Probiotics & High-Strength Gut Health

Home of the Original De Simone Formulation, plus expert-selected supplements.

Shop CDS22-formula

Official De Simone Formulation Distributor – Republic of Ireland

Probiotic.ie: Sole Official De Simone Distributor – Republic of Ireland

✅ Original De Simone formulation (includes CDS22-formula)

✅ Clinically studied 8-strain probiotic formulation

✅ Sole official distributor for the Republic of Ireland


Probiotic.ie is the sole official distributor of De Simone formulation probiotic products, including CDS22-formula, in the Republic of Ireland. All retail, wholesale, and clinical supply for Ireland is fulfilled through our Irish operation, with local fulfilment, customer support, and nationwide supply.

Previously marketed under names such as Vivomixx and VSL#3, CDS22-formula continues the original De Simone formulation developed by Professor Claudio De Simone. It is supplied in Ireland exclusively through authorised distribution, preserving the documented formulation lineage.

Shop CDS22-formula About the De Simone formulation

Probiotic.ie: Sole Official Supplier of the De Simone CDS22-formula Range in Ireland

The complete CDS22-formula range, based on the original De Simone formulation developed by Professor Claudio De Simone, supplied exclusively by Probiotic.ie as the sole official distributor for the Republic of Ireland

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

€ 73.50 EUR

CDS22-formula Probiotic 450B CFU | Original De Simone Formulation | 12 Sachets

CDS22-formula Probiotic 450B CFU | Original De Simone Formulation | 12 Sachets

€ 25.95 EUR

CDS22-formula Probiotic 112B CFU | Original De Simone Formulation | 20 Capsules
Save 4%

CDS22-formula Probiotic 112B CFU | Original De Simone Formulation | 20 Capsules

€ 23.95 EUR Regular price € 24.95 EUR

CDS22-formula Infant Drops – Original De Simone Formulation (2×5 ml Bottles)

CDS22-formula Infant Drops – Original De Simone Formulation (2×5 ml Bottles)

€ 17.95 EUR

Expert Selected. Evidence Led.

Expert-Selected Supplements Trusted by Irish Customers

Beyond CDS22-formula, the same Irish team behind Ireland’s sole official De Simone distributor carefully selects a focused range of supplements for quality, formulation standards, and real-world use in Ireland. From well-researched ingredients like Berberine HCl and Lion’s Mane Mushroom to essential vitamins and minerals, every product is Probiotic.ie-curated, standards-compliant, and chosen based on evidence and Irish customer demand.

Explore All Supplements

Probiotic.ie’s Most Chosen Supplements in Ireland

Selected by Probiotic.ie based on repeat purchase, long-term use, and Irish customer demand.

Swanson Berberine HCl 400 mg – Premium Herbal Supplement - 60 Caps

Swanson Berberine HCl 400 mg – Premium Herbal Supplement - 60 Caps

€ 22.95 EUR

Swanson Lion’s Mane Mushroom 500mg – 60 Capsules

Swanson Lion’s Mane Mushroom 500mg – 60 Capsules

€ 16.95 EUR

Swanson Ashwagandha 450mg - 100 Caps
Save 11%

Swanson Ashwagandha 450mg - 100 Caps

€ 15.95 EUR Regular price € 17.95 EUR

Swanson Full Spectrum Milk Thistle 500mg – 100 Capsules
Save 8%

Swanson Full Spectrum Milk Thistle 500mg – 100 Capsules

€ 15.45 EUR Regular price € 16.95 EUR

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

CDS22-Formula | Original De Simone Formulation Probiotic | 450 Billion CFU | 36 Sachets | One Month+ Pack |

€ 73.50 EUR

NOW NAC 600mg – N-Acetyl Cysteine 100 Veg Capsules
Save 8%

NOW NAC 600mg – N-Acetyl Cysteine 100 Veg Capsules

€ 22.95 EUR Regular price € 24.95 EUR

Swanson Sulforaphane from Broccoli 400 mcg – 60 Veg Capsules
Save 8%

Swanson Sulforaphane from Broccoli 400 mcg – 60 Veg Capsules

€ 15.45 EUR Regular price € 16.95 EUR

Swanson Full Spectrum Saw Palmetto 540 mg 100/250 Caps
Save 3%

Swanson Full Spectrum Saw Palmetto 540 mg 100/250 Caps

From € 15.45 EUR Regular price € 15.95 EUR

New Supplements at Probiotic.ie (Ireland)

Each new food supplement is reviewed by Probiotic.ie for ingredient quality, regulatory compliance, and fit with our evidence-led range.

Only products that meet these standards are added to this collection | Updated regularly as new, standards-compliant supplements arrive.

Swanson Moringa Oleifera 400 mg 60 Capsules | Food Supplement
Save 15%

Swanson Moringa Oleifera 400 mg 60 Capsules | Food Supplement

€ 10.95 EUR Regular price € 12.95 EUR

NOW Foods Taurine Double Strength 1000 mg 250 Veg Capsules | Food Supplement
Save 8%

NOW Foods Taurine Double Strength 1000 mg 250 Veg Capsules | Food Supplement

€ 29.95 EUR Regular price € 32.75 EUR

AllNutrition Berberine HCl Plus 90 Caps | Food Supplement

AllNutrition Berberine HCl Plus 90 Caps | Food Supplement

€ 19.95 EUR

Swanson Berberine Complex with Cinnamon, Gymnema & Fenugreek | 90 Veg Caps

Swanson Berberine Complex with Cinnamon, Gymnema & Fenugreek | 90 Veg Caps

€ 24.95 EUR

Why Irish Customers Trust Probiotic.ie

We’re an Irish-owned specialist store focused on evidence-led probiotics and supplements, including Ireland’s exclusive access to the original De Simone formulation.

Since 2019, we’ve helped thousands of customers across Ireland choose products based on formulation quality, clinical heritage, and real-world use — not trends or marketing claims.

Our service is independently rated 4.9 out of 5 on Trustpilot, based on hundreds of verified Irish customer reviews, reflecting consistent feedback on fast delivery, product quality, and responsive support.

Every product we stock is selected by us, handled correctly, and shipped from Ireland, with local customer support if you ever need help.

You’re not buying from a faceless marketplace. You’re buying from a real Irish team that stands behind every order.

⭐ 4.9★ independent rating on Trustpilot
🇮🇪 Irish-owned and operated since 2019
🧪 Evidence-led product selection
📦 Fast delivery from Ireland
💬 Real human customer support

Start With the Right Place

Choosing supplements shouldn’t be confusing. We’ve organised our range into four clear starting points, depending on what you’re looking for.

Probiotic.ie is Ireland’s evidence-led supplements store. Start with our official De Simone CDS22-formula or explore trusted supplement paths below.

Start with CDS22-formula Probiotic | The original De Simone formulation, clinically established and selected as our lead probiotic.

Gut Health Essentials | Evidence-led supplements commonly used to support digestion, balance, and everyday gut care.

Most Trusted Supplements in Ireland | Our most chosen supplements, based on verified customer use and consistent reorder demand.

Expert Guides & How to Choose | Clear, independent guides to help you choose supplements with confidence.

Probiotic.ie Expert Gut Health & Supplement Guides for Ireland

Berberine + Probiotics Ireland: Synergy for Gut, Blood Sugar and Weight

By Darren Grant on Jan 27, 2026

Berberine and probiotics are often taken together. This Ireland-first guide explains the evidence, the safety considerations, and simple timing options without hype.

Read more
Berberine Ireland: Evidence, Benefits, Side Effects & Where to Buy (2026)

By Darren Grant on Jan 24, 2026

 clear, evidence-led guide to berberine in Ireland. Learn what berberine is, what studies show, possible side effects, and how to choose a good-value supplement.

Read more
Probiotics Ireland: A Clear, Evidence-Based Guide for Irish Consumers

By Darren Grant on Dec 17, 2025

A neutral, evidence-based guide explaining probiotics in Ireland, how products differ, regulation, buying tips, and common questions for Irish consumers.

Read more
Best Probiotic for UC, IBS & Pouchitis (Ireland Evidence-Based Guide)

By Darren Grant on Dec 12, 2025

Evidence-led Ireland guide to probiotics for ulcerative colitis, pouchitis and IBS. Learn where studies are strongest, what varies by formulation, and what to ask your GP or gastro team.

Read more
CDS22 vs Optibac Every Day: Evidence-Based Probiotic Comparison (Ireland)

By Darren Grant on Dec 12, 2025

A factual Ireland-focused comparison of CDS22-formula 450B sachets and Optibac Every Day capsules, covering strains, CFU strength, evidence context, and practical use.

Read more
CDS22 vs Symprove: Evidence-Based Probiotic Comparison for Ireland

By Darren Grant on Dec 11, 2025

Independent Irish comparison of CDS22-formula and Symprove covering strain profiles, CFU strength, delivery format and clinical evidence. A clear, factual guide for Irish readers.

Read more